“DM1 is a progressive disease with no treatment options available. “Our collaboration with Vertex represents an important step for Entrada as we work to make intracellular therapeutics a reality through our novel EEV approach,” said Dipal Doshi, President and Chief Executive Officer of Entrada Therapeutics. Working together, we believe we have the opportunity to develop a transformative treatment for this devastating disease.” “Entrada’s innovative EEV approach, the significant progress in their DM1 program, and the potential for it to reach the clinic in the near-term hold exciting potential for patients. “Vertex’s strategy is to discover and develop transformative medicines for people with serious diseases, and DM1 has therefore been a disease area of interest to Vertex for some time,” said David Altshuler, M.D., Ph.D., Executive Vice President, Global Research, and Chief Scientific Officer of Vertex. The collaboration includes Entrada’s program for DM1, ENTR-701, which is in late-stage preclinical development. (Nasdaq: TRDA) today announced a global collaboration focused on discovering and developing intracellular Endosomal Escape Vehicle (EEV™) therapeutics for myotonic dystrophy type 1 (DM1). Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Entrada Therapeutics, Inc. Associazioni Familiari Vittime Terrorismo e Stragi.ANM - Associazione Nazionale Magistrati.ANAC - Autorità Nazionale Anticorruzione.CSM - Consiglio Superiore della Magistratura.
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